Critical Junctures in Genetic Medicine: The Transformation of DNA Lab Science to Commercial Pharmacogenomics

Stephanie S. Turner University of Houston - Downtown

Abstract

Genetic medicine, which consists mostly of screening tests for certain heritable diseases but may soon include treatment for heritable diseases based on molecular genetics, is made possible by two critical junctures in the textual representation of medical subjects. The first is the transformation of organic human genetic material into computationally sophisticated data, and the second is the subsequent conversion of these vast quantities of genetic data into intellectual property through gene patenting and screening-test marketing. This article examines these representational changes in medical subjects through an intertextual and rhetorical analysis of the documentation surrounding the discovery, patenting, and marketing of the breast cancer susceptibility gene BRCA1 by the biotechnology company Myriad Genetics. It identifies the impact of these changes on the analysis of the risks and benefits associated with screening for heritable diseases.

Journal
Journal of Business and Technical Communication
Published
2005-07-01
DOI
10.1177/1050651905275619
CompPile
Open Access
Closed
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Cited by in this index (3)

  1. Journal of Business and Technical Communication
  2. Journal of Business and Technical Communication
  3. Journal of Technical Writing and Communication

References (56) · 3 in this index

  1. Policy statements
  2. Report 9 of the Council on Scientific Affairs: Patenting of genes and their mutations
  3. 10.1038/nrg909
     ↗
  4. Journal of Business and Technical Communication
  5. Journal of Business and Technical Communication
Show all 56 →
  1. 10.1172/JCI20113
     ↗
  2. Mission and guidelines
  3. Policy on genetic testing for breast cancer susceptibility
  4. Brenner v. Manson, 383 U.S. 519 (1966).
  5. 10.1038/35042087
     ↗
  6. 10.1056/NEJMra012577
     ↗
  7. NewScientist.com
  8. 10.1038/35093580
     ↗
  9. 10.1086/301784
     ↗
  10. 10.1080/1360083042000190625
     ↗
  11. 10.1111/1467-9566.00151
     ↗
  12. Health care and intellectual property rights
  13. Wetwares: Experiments in postvital living
  14. Journal of Business and Technical Communication
  15. Emory Law Journal
  16. 10.1162/152651602760249969
     ↗
  17. 10.1126/science.7939630
     ↗
  18. 10.1126/science.2270482
     ↗
  19. Texas Intellectual Property Law Journal
  20. 10.1126/science.274.5287.496
     ↗
  21. Genetics researchers collaborate with Utah families
  22. 10.2307/378062
     ↗
  23. The century of the gene
     ↗
  24. 10.1002/(SICI)1096-8628(19970822)71:3<289::AID-AJMG8>3.0.CO;2-P
     ↗
  25. International Intellectual Property Institute
  26. MAMM: Women, Cancer, and Community
  27. 10.1126/science.7545954
     ↗
  28. 10.1353/con.2004.0022
     ↗
  29. Moore v. Regents of the University of California, 249 Cal. (1990).
  30. 10.1016/S0065-2660(03)50002-5
     ↗
  31. 10.1177/030631295025001004
     ↗
  32. Research
  33. Understanding inherited breast and ovarian cancer
  34. Annual report
  35. Myriad Genetics identifies six new drug targets
  36. Information for healthcare professionals: Benefits of BRACAnalysis® testing
  37. Myriad Genetics and LabCorp form exclusive predictive medicine marketing alliance
  38. 10.1038/35080583
     ↗
  39. Gattaca
  40. 10.1126/science.278.5340.1068
     ↗
  41. 10.1162/152651602760250011
     ↗
  42. White paper on proteomics and genomics: Meeting utility requirements
  43. 10.1126/science.8430309
     ↗
  44. Linked breast and ovarian cancer susceptibility gene
  45. Myriad Genetics: Executing the vision of molecular medicine
  46. 10.1353/pmc.2003.0010
     ↗
  47. Biomedia
  48. Federal Register
  49. 10.1136/bmj.323.7318.888
     ↗
  50. Health Law Journal
  51. 10.1056/NEJMra012284
     ↗